Drug Allergy
"The Clinica has developed the technique of the basophil activation test to analyze in the laboratory possible allergies to drugs and thus correctly evaluate the convenience of carrying out tolerance tests".
DR. GABRIEL GASTAMINZA LASARTE
DIRECTOR. ALLERGY AND IMMUNOLOGY DEPARTMENT
How do you know if you have a drug allergy?
Suspected drug allergy is one of the most frequent visits to an allergology specialist.
Drugs are capable of causing adverse reactions of all kinds, not just allergic ones. In addition, the drug is often blamed for a wide range of symptoms, which can be confused with an allergic reaction, but which are caused by a coincident cause.
Allergic reactions to drugs are unpredictable reactions of varying severity, some of which are life-threatening. Any medication can cause allergic reactions.
Among the medicines that most frequently cause allergic reactions are antibiotics, aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs), iodine contrast agents for radiology, anticonvulsants, certain antihypertensives, eye drops and hormones, and even, exceptionally, corticosteroids.
What are the symptoms of drug allergy?
The clinical manifestations that they produce are varied but almost always they are eruptions in the skin, being the most frequent the urticaria (rashes) and the angioedema (swelling of soft parts) in immediate reactions, or the exanthema (rash) in delayed reactions.
These can be life-threatening reactions (anaphylaxis) or severe skin reactions (scalding syndromes and others).
Usually, the symptoms or skin lesions disappear within a few hours after the drug is withdrawn, although, depending on the type of reaction, they may also persist for days or weeks.
The most common symptoms are:
- Hives
- Swelling of soft parts (tongue, lips, eyelids...)
- Rash
- Itchy skin or eyes
Do you have any of these symptoms?
You may have a drug allergy
What are the symptoms of drug allergy?
The clinical manifestations that they produce are varied but almost always they are eruptions in the skin, being the most frequent the urticaria (rashes) and the angioedema (swelling of soft parts) in immediate reactions, or the exanthema (rash) in delayed reactions.
These can be life-threatening reactions (anaphylaxis) or severe skin reactions (scalding syndromes and others).
Usually, the symptoms or skin lesions disappear within a few hours after the drug is withdrawn, although, depending on the type of reaction, they may also persist for days or weeks.
The most common symptoms are:
- Hives
- Swelling of soft parts (tongue, lips, eyelids...)
- Rash
- Itchy skin or eyes
How is drug allergy treated?
Our Immunotherapy Unit is formed by doctors and nurses with great experience in this treatment
The goal of treatment is to relieve symptoms and prevent a serious reaction.
Drug treatment may include antihistamines, bronchodilators, and corticosteroids applied to the skin or given orally or intravenously.
The offending drug and other similar medications should be avoided.
If a medication to which a person is allergic is essential, desensitization or tolerance induction may be performed.
La desensibilización consiste en administrar a un paciente el fármaco al que es alérgico a través de dosis inicialmente muy pequeñas y progresivamente crecientes a intervalos fijos de tiempo, hasta alcanzar la dosis terapéutica. No supone que el paciente deje de ser alérgico, si no que "engaña" al sistema inmunológico para evitar que se desencadene una reacción, logrando una tolerancia temporal del medicamento.
Se realiza cuando no existe una alternativa adecuada a ese tratamiento farmacológico. Los casos más frecuentes están relacionados con los antibióticos (en especial penicilinas para algunas infecciones sin otros antibióticos válidos) y quimioterápicos (sobre todo platinos y taxanos).
La realización de una desensibilización es compleja, requiere la coordinación de muchas personas y departamentos, y es un procedimiento de riesgo, que requiere un estricto control por personal con experiencia. En la Clínica Universidad de Navarra tenemos una amplia experiencia en la realización de desensibilizaciones con medicamentos.
Where do we treat it?
IN NAVARRE AND MADRID
Department of Allergology
of the Clínica Universidad de Navarra
The Department of Allergy and Immunology of the Clinic is part of the Global Allergy and Asthma European Network, composed of the 25 best departments of Allergy in Europe, chosen for their scientific excellence, multidisciplinary work, teaching and international activities.
We have the most advanced diagnostic techniques, we are at the forefront of research and we collaborate with the best experts. We have more than 50 years of experience in the field.
What diseases do we treat?
Why at the Clinica?
- More than 50 years of experience.
- Pioneers in the technique of molecular diagnosis by microarray.
- Nursing specialized in allergic diseases and their care.
Our team of professionals
Allergology specialists with experience in treating drug allergy
