Waldenström macroglobulinemia associated with cutaneous lesions and type I cryoglobulinemia
Magazine: Actas Dermo-Sifiliográficas
Date: Mar 1, 2008Pathological Anatomy [SP] Hematología y Hemoterapia [SP] Dermatology
Waldenström macroglobulinemia is a blood dyscrasia characterized by monoclonal proliferation of B cells in the bone marrow, lymph nodes, and spleen. Patients with this disease show elevated serum levels and tissue deposition of monoclonal immunoglobulin (Ig) M produced by these aberrant cells.
We present the case of a patient with Waldenström macroglobulinemia who suffered cutaneous lesions resulting from deposition of k light chains of IgM and clinical manifestations secondary to associated type I cryoglobulinemia. We discuss the different pathological cutaneous processes caused by IgM in Waldenström macroglobulinemia.
CITATION Actas Dermosifiliogr. 2008 Mar;99(2):138-44
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