Scientific publications

Use of Intra-aortic Balloon Pump as a Bridge to Heart Transplant in Spain: Results From the ASIS-TC Study

Barge-Caballero E (1), González-Vílchez F (2), Delgado JF (3), Mirabet-Pérez S (4), González-Costello J (5), Pérez-Villa F (6), Martínez-Sellés M (7), Segovia-Cubero J (8), Hervás-Sotomayor D (9), Blasco-Peiró T (10), De la Fuente-Galán L (11), Lambert-Rodríguez JL (12), Rangel-Sousa D (13), Almenar-Bonet L (14), Garrido-Bravo IP (15), Rábago-Juan-Aracil G (16), Muñiz J (17), Crespo-Leiro MG (18(.

(1) Servicio de Cardiología, Complejo Hospitalario Universitario A Coruña (CHUAC), Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.
(2) Servicio de Cardiología, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.
(3) Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain; Servicio de Cardiología, Hospital Universitario 12 de Octubre, Instituto de Investigación i+12, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
(4) Servicio de Cardiología, Hospital Santa Creu i Sant Pau, Barcelona, Spain.
(5) Servicio de Cardiología, Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
(6) Servicio de Cardiología, Hospital Clinic i Provincial, Barcelona, Spain.
(7) Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain; Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, Universidad Complutense, Universidad Europea, Madrid, Spain.
(8) Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain; Servicio de Cardiología, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain.
(9) Servicio de Cirugía Cardiaca, Hospital Universitario Reina Sofía, Córdoba, Spain.
(10) Servicio de Cardiología, Hospital Universitario Miguel Servet, Zaragoza, Spain.
(11) Servicio de Cardiología, Hospital Clínico Universitario, Valladolid, Spain.
(12) Servicio de Cardiología, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain; Universidad Católica San Antonio, Murcia, Spain.
(13) Servicio de Cardiología, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
(14) Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
(15) Servicio de Cardiología, Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain.
(16) Servicio de Cirugía Cardiaca, Clínica Universidad de Navarra, Pamplona, Navarra, Spain.
(17) Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain; Instituto Universitario de Ciencias de la Salud, Universidad de A Coruña, A Coruña, Spain.
(18) Servicio de Cardiología, Complejo Hospitalario Universitario A Coruña (CHUAC), Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, Madrid, Spain.

Magazine: Revista Española de Cardiología

Date: Aug 13, 2018

Cardiac Surgery [SP]

Introduction and objectives

In Spain, intra-aortic balloon pump (IABP) has been used frequently as a bridge to urgent heart transplant (HT). We sought to analyze the clinical outcomes of this strategy.

Methods

We conducted a case-by-case, retrospective review of clinical records of 281 adult patients listed for urgent HT under IABP support in 16 Spanish institutions from 2010 to 2015. Pre- and post-transplant survival and adverse clinical events were analyzed.

Results

A total of 194 (69%, 95%CI, 63.3-74.4) patients were transplanted and 20 (7.1%, 95%CI, 4.4-10.8) died during a mean period of IABP support of 10.9 ± 9.7 days. IABP support was withdrawn before an organ became available in 32 (11.4%) patients. Thirty-five (12.5%, 95%CI, 8.8-16.9) patients transitioned from IABP to full-support mechanical devices. Mean urgent waiting list time increased from 5.9 ± 6.3 days in 2010 to 15 ± 11.7 days in 2015 (P = .001). Post-transplant survival rates at 30-days, 1-year, and 5-years were 88.1% (95%CI, 85.7-90.5), 76% (95%CI, 72.9-79.1), and 67.8% (95%CI, 63.7-71.9), respectively. The incidence rate of major adverse clinical outcomes—device dysfunction, stroke, bleeding or infection—during IABP support was 26 (95%CI, 20.6-32.4) episodes per 1000 patient-days. The incidence rate of IABP explantation due to complications was 7.2 (95%CI, 4.5-10.8) cases per 1000 patient-days.

Conclusions

In a setting of short waiting list times, IABP can be used to bridge candidates to urgent HT with acceptable postoperative results, but there were significant rates of adverse clinical events during support.

CITATION  Rev Esp Cardiol (Engl Ed). 2018 Aug 13. pii: S1885-5857(18)30299-8. doi: 10.1016/j.rec.2018.07.003

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