Scientific publications 

The use of SWI-MRI to differentiate between seizures and transient ischemic attacks in a patient with cerebral amyloid angiopathy

Gasca-Salas C, García de Eulate R, Pastor P.
Departamento de Neurología, Clínica Universidad de Navarra, Pamplona, 31008, Spain

Magazine: Anales del Sistema Sanitario de Navarra

Date: Aug 1, 2011

Neurology [SP] Radiology [SP]

Cerebral amyloid angiopathy (CAA) is characterized by the deposit of β-amyloid on the walls of small and medium-sized arteries of the cerebral cortex and leptomeninges causing cerebral bleeding. Clinical presentations may include transient neurological events for which differential diagnosis can be difficult.

We report a subject with a medical history of a recent stroke who presented somesthetic seizures mimicking transient ischemic attacks owing to CAA microbleeding. Antiplatelet treatment was reduced and after lamotrigine was commenced the episodes disappeared. Susceptibility-weighted magnetic resonance imaging was very helpful for diagnosis (SWI-MRI).

CAA microbleeding can be manifested in the form of seizures mimicking focal transient sensitive neurological deficits that can be erroneously attributed to cerebral ischemia. The present case report suggests that, despite the presence of a past medical history of strokes, neurologists should consider CAA microbleeding as a possible cause of pseudo-transient ischemic attacks. High-resolution neuroimaging including SWI-MRI imaging can be helpful in identifying cortical microbleedings. In this way, the start or increase of antiplatelet treatment can be avoided, and the risk of potentially fatal complications minimized.

CITATION  An Sist Sanit Navar. 2011 mayo-agosto;34(2):317-321

you maybe interested


The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra


The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.

Imagen profesionales de la Clínica Universidad de Navarra


Learn why we are different from other healthcare centers. Quality, speed, comfort and results.

Imagen del edificio de la Clínica Universidad de Navarra