Scientific publications

Surgical evaluation of a liver transplant program. Experiences with the first 45 cases

Jun 1, 1989 | Magazine: Revista Española de Enfermedades del Aparato Digestivo

Cienfuegos JA, Pardo F, Pérez Mora N, Herrera J, Pereira F, Sánchez Turrión V, Ardáiz J, De Vicente E, Olivares P, Murcia J, et al.

The cumulative experience in liver transplantation since the introduction of cyclosporine A has confirmed its efficacy in the treatment of diverse liver diseases in children and adults. In the present study we review the surgical aspects of 45 transplants performed in 39 patients (17 children and 22 adults).

Immunosuppressive treatment consisted of cyclosporine A, steroids and monoclonal antibodies (OKT3) in rejection unresponsive to steroids. The actuarial survival rate one year after transplantation was 74%. In the course of development of the program, the elective use of veno-venous bypass during the anhepatic phase in adults was confirmed as useful. Among pediatric transplantations there were numerous arterial malformations (31.5%) in donor organs, which, with the malformations associated in receptors, made allograft reconstruction difficult.

Our results confirm those reported by other groups, as well as the importance of specialized training for this type of intervention.

CITATION  Rev Esp Enferm Apar Dig. 1989 Jun;75(6 Pt 2):635-44