Scientific publications

Sarcomatoid carcinoma and orbital apex syndrome

Jul 1, 2006 | Magazine: European Journal of Ophthalmology

Sadaba LM, García-Layana A, Garcia-Gomez PJ, Salinas-Alaman A.

To report a case of sarcomatoid carcinoma and orbital apex syndrome in a previously healthy adult.


A previously healthy 45-year-old man presented with exophthalmos of the left eye and a mass visible through his left nostril. A biopsy was performed and immunohistochemistry was used to confirm the diagnosis of the tumor. The patient was treated with chemotherapy and radiotherapy.

After treatment, we observed a substantial reduction in the size of the mass, but side effects of treatment developed. The visual acuity of the left eye was no light perception. Eight months later, the patient presented with bone and liver metastases, and he died 4 months later.

Sarcomatoid carcinoma is an aggressive tumor that can produce compressive symptoms with very poor visual and survival prognoses. A cranio-orbital computed tomography scan should be performed when patients present with symptoms of conjunctivitis and orbital apex syndrome.

CITATION  Eur J Ophthalmol. 2006 Jul-Aug;16(4):608-10