Scientific publications

Respiratory syncytial virus hospitalization in children in northern Spain

Viguria N (1,2), Martínez-Baz I (2,3,4), Moreno-Galarraga L (1,2), Sierrasesúmaga L (5), Salcedo B (6), Castilla J (2,3,4).

(1) Department of Pediatrics, Complejo Hospitalario de Navarra, Pamplona, Spain.
(2) Instituto de Investigación Sanitaria de Navarra, IdiSNA, Pamplona, Spain.
(3) Instituto de Salud Pública de Navarra, Pamplona, Spain.
(4) CIBER Epidemiología y Salud Pública, Pamplona, Spain.
(5) Clínica Universidad de Navarra, Pamplona, Spain.
(6) Servicio de Gestión, Información y Evaluación, Complejo Hospitalario de Navarra, Pamplona, Spain.

Magazine: PLoS One

Date: Nov 15, 2018

Pediatría [SP]


Understanding respiratory syncytial virus (RSV) morbidity may help to plan health care and future vaccine recommendations. We aim to describe the characteristics and temporal distribution of children diagnosed with RSV admitted in a Spanish hospital.


Descriptive study for which the hospital discharges of children < 5 years of age with RSV infection were analyzed. The information was extracted from the hospital discharge database of a reference pediatric hospital in northern Spain for the 2010-2011 to 2014-2015 RSV seasons.


Six hundred and forty-seven hospitalizations of children with RSV infection were analyzed, 94% of which occurred between the second week of November and the last week of March. Most children (72%) were under one year of age and 95% were previously healthy infants. Infants born from October to December had the highest risk of hospitalization in the first year of life.

The median length of hospital stay of children with and without comorbidities was six and three days, respectively. 6.5% of the hospitalized cases were admitted to the pediatric intensive care unit; this percentage was higher among children < 2 months (adjusted odds ratio 4.15; 95% confidence interval: 1.37-12.61) or with comorbidities (adjusted odds ratio 4.15; 95% confidence interval: 1.53-11.28). The case lethality was 0.3%.


The risk of hospitalizations for RSV is high during the first year of life and increases among infants born in the fall. Being under two months of age and presenting comorbidities are the main risk factors associated to pediatric intensive care unit admission.

CITATION  PLoS One. 2018 Nov 15;13(11):e0206474. doi: 10.1371/journal.pone.0206474

you maybe interested


The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra


The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.

Imagen profesionales de la Clínica Universidad de Navarra


Learn why we are different from other healthcare centers. Quality, speed, comfort and results.

Imagen del edificio de la Clínica Universidad de Navarra