Scientific publications

Rat atrial natriuretic peptide stimulates K+ fluxes in human erythrocytes

Jul 1, 1989 | Magazine: The European Journal of Pharmacology

Esparza N., Díez J.
Servicio de Nefrología, Clínica Universitaria, Universidad de Navarra, Spain.


Ouabain- and bumetanide-resistant potassium fluxes were measured in human erythrocytes incubated in a medium containing calcium and a calcium ionophore.

Pharmacological concentrations of rat atrial natriuretic peptide stimulated these fluxes. Although human erythrocytes lack atrial natriuretic peptide receptors, our results suggest that the hormone can modify transmembrane K+ movements.

CITATION  Eur J Pharmacol. 1989 Jul 18;166(2):349-52

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