Primary central nervous system lymphoma treated with rituximab plus temozolomide in a second line schedule
M. Santisteban (1), Y. Nieto (1), S. De la Cruz (1), J. Aristu (2), J. L. Zubieta (3) and O. Fernández Hidalgo (1)
(1) Departmento de Oncología Médica, Clínica Universitaria de Navarra, Avda. Pío XII, 36, ES-31008 Pamplona, Spain
(2) Departamento de Radioterapia, Clínica Universitaria de Navarra, Pamplona, Spain
(3) Servicio de Radiología, Clínica Universitaria de Navarra, Pamplona, Spain
Magazine: Clinical and Translational Oncology
Date: Jul 1, 2007Radiation Oncology Radiology [SP] Medical Oncology
We report a case of primary CNS lymphoma treated with high-dose methotrexate in the first line.
After disease progression the patient received cranial radiotherapy with concomitant temozolomide, followed by rituximab plus temozolomide, with complete remission of the disease maintained for at least two years and without major toxicity.
CITATION Clin Transl Oncol. 2007 Jul;9(7):465-7
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