Scientific publications

Oxygen-derived free radicals. Their role in cardiology

Iglesias I., García Bolao I., Aparici M., Alzamora P., Alegría E.
Dpto. de Cardiología, Facultad de Medicina, Universidad de Navarra, Pamplona.

Magazine: Revista de Medicina de la Universidad de Navarra

Date: Apr 1, 1990


Oxygen-derived free radicals are highly reactive molecules characterized by the presence of an unpaired electron in one of its outer orbitals.

They have been found responsible for some pathologic phenomenons which in the field of cardiology, occurs during tissue reperfusion of a previously ischemic area. Ischemia predisposes an outburst in the production of these molecules upon the reintroduction of oxygen during reperfusion. Animal experimental models have been designed to reduce the damages induced by free radicals using various pharmacologic agents.

It is probable that these agents may form a part of the conventional treatment of certain cardiac pathologies in the future.

CITATION  Rev Med Univ Navarra. 1990 Apr-Jun;34(2):101-7

you maybe interested


The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra


The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.

Imagen profesionales de la Clínica Universidad de Navarra


Learn why we are different from other healthcare centers. Quality, speed, comfort and results.

Imagen del edificio de la Clínica Universidad de Navarra