Scientific publications

Mechanisms of cell death in Alzheimer's disease

Jan 1, 1997 | Magazine: Revista de Medicina de la Universidad de Navarra

Luquin M.R., Martínez-Vila E., Saldise L.
Departamento de Neurología y Neurocirugía, Clínica Universitaria, Facultad de Medicina, Universidad de Navarra

Molecular mechanisms involved in neuronal degeneration in Alzheimer's disease remain still unknown.

A toxic effect induced by beta amyloid, oxidative stress, excitotoxicity and alterations in signal transduction mechanisms are the main factors linked to neuronal death. In addition, it has been suggested that apoptosis may also participate as a part of the cascade of events resulting in neurodegeneration.

CITATION  Rev Med Univ Navarra. 1997 Jan-Mar;41(1):34-45

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