Scientific publications

Liver transplantation in colorectal metastases. Is there an indication for this procedure?

Aug 4, 2023 | Magazine: Revista Española de Enfermedades Digestivas

Javier A Cienfuegos  1 , Gabriel Zozaya  2 , Fernando Rotellar  2


Abstract

Almost 25% of patients with colorectal cancer present metastases at the time of diagnosis and 50% go on to develop metastases in the course of the disease. Surgical resection is the only curative treatment although only between 20% and 30% of patients present resectable lesions.

Although liver transplantation is contraindicated in unresectable metastases of colorectal cancer, ever since the publication of the results of a pilot study there has been renewed interest in transplantation in these patients.

In two consecutive trials overall and recurrence-free 5-year survival rates of 83% and 35% respectively, have been reported, Currently several trials are ongoing which are expected to allow the patient selection criteria for the indication of liver transplantation to be refined.

CITATION  Rev Esp Enferm Dig. 2023 Aug 4.  doi: 10.17235/reed.2023.9873/2023