Scientific publications

Late-onset periodic asystolia during vagus nerve stimulation

Iriarte J, Urrestarazu E, Alegre M, Macías A, Gómez A, Amaro P, Artieda J, Viteri C.
Epilepsy Section, Clinica Universitaria, University of Navarra, Pamplona, Spain

Magazine: Epilepsia

Date: Dec 4, 2008

Neurology [SP] Neurophysiology [SP]

Cardiac changes may occasionally occur during vagus nerve stimulation (VNS) used in epileptic patients. As they can be potentially life-threatening, it is important to detect them, and this is why an intraoperative test is performed during the implantation.

Few cases of asystole during this test have been described. Only one patient with late-onset bradyarrythmia caused by VNS has been reported. This patient had been implanted 2 years and 4 months before the episode. We present another case of late asystole in a patient whose VNS had been implanted 9 years before the arrhythmia onset. In our patient, each run of stimulation produced bradyarrhythmias and very often severe asystolia due to atrium-ventricular block.

CITATION Epilepsia. 2009 Apr;50(4):928-32

you maybe interested


The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra


The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.

Imagen profesionales de la Clínica Universidad de Navarra


Learn why we are different from other healthcare centers. Quality, speed, comfort and results.

Imagen del edificio de la Clínica Universidad de Navarra