Infiltrating bladder carcinoma with metastatic lymph node involvement: radical treatment and survival
de Castro Barbosa F, Sánchez de la Muela P, Rosell Costa D, Aguera Fernández L, Isa Kroon W, Robles García JE, Berián Polo JM.
Departamento de Urología, Facultad de Medicina, Universidad de Navarra, Pamplona
Presentation of the results obtained from the study of 64 patients with T2-4 stage vesical carcinoma, treated with radical cystectomy, local lymphadenectomy, with and without complementary radiotherapy, with and without neoadjuvant chemotherapy.
The univariate study of 19/64 patients with microscopic nodular disease revealed a significant relationship with the pathological stage but not with the clinical stage. The multivariate study demonstrated that the most relevant prognostic factors are a decrease in tumoral stage (P) and the presence of vascular and/or lymphatic involvement in the TUR-biopsy.
The analysis of survival confirms the poor prognosis of patients with metastatic nodular involvement, in spite of the association of pelvic radiotherapy or neoadjuvant chemotherapy to the treatment.
CITATION Actas Urol Esp. 1992 Jan;16(1):58-62