Scientific publications

How Could 90 Y-Loaded Microsphere Distribution Be Optimized?

Jul 1, 2022 | Magazine: Cardiovascular and Interventional Radiology

Jorge Aramburu  1   2 , Raúl Antón  3   4   5 , Bruno Sangro  5   6

In this issue of CVIR, Maxwell et al. [1] elucidate that radioembolization outcomes can be improved by optimizing 90Y-loaded microsphere density (i.e., the number of microspheres deposited per unit treated volume).

Specifically, they claim that patients with hypervascular tumors will respond better to a low microsphere density radioembolization, typically achieved with glass microspheres, and patients with less vascular tumors will benefit more from a high microsphere density radioembolization, typically achieved with resin microspheres.

Therefore, this study could be seen as a tumor vascularity-based criterion to choose between resin and glass microspheres.

CITATION  Cardiovasc Intervent Radiol. 2022 Jul;45(7):970-971. doi: 10.1007/s00270-022-03180-5. Epub 2022 Jun 9. 

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