Scientific publications
Hepatocyte-stellate cell synapse in alcohol-induced steatosis: another role for endocannabinoids. Scientific Publication
Jan 1, 2020
| Magazine: Nature Reviews. Gastroenterology and Hepatology
Josepmaria Argemi (1), Ramon Bataller (2)SA.
A new study demonstrates a novel role for an endocannabinoid in promoting hepatocyte steatosis. The study describes a mode of bidirectional communication between the alcohol-injured hepatocyte and the glutamate-activated hepatic stellate cell.
This intercellular communication represents a novel targetable pathogenic mechanism that could lead to new strategies to prevent fatty liver disease progression to cirrhosis.
CITATION Nat Rev Gastroenterol Hepatol. 2020 Jan;17(1):5-6.
doi: 10.1038/s41575-019-0233-8
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