Hepatocyte-stellate cell synapse in alcohol-induced steatosis: another role for endocannabinoids
Josepmaria Argemi (1), Ramon Bataller (2)SA.
A new study demonstrates a novel role for an endocannabinoid in promoting hepatocyte steatosis. The study describes a mode of bidirectional communication between the alcohol-injured hepatocyte and the glutamate-activated hepatic stellate cell.
This intercellular communication represents a novel targetable pathogenic mechanism that could lead to new strategies to prevent fatty liver disease progression to cirrhosis.
CITA DEL ARTÍCULO Nat Rev Gastroenterol Hepatol. 2020 Jan;17(1):5-6.