Gene therapy of liver cancer
Hernández-Alcoceba R, Sangro B, Prieto J.
Division of Gene Therapy and Hepatology, Foundation for Applied Medical Research-CIMA, University of Navarra, Pamplona, Spain
Gene therapy of liver cancer covers a variety of gene transfer strategies aimed to the treatment of patients with primary and secondary liver tumors, including gene directed enzyme/pro-drug therapy, inhibition of oncogenes and restoration of tumor-suppressor genes, immunotherapy, anti-angiogenesis and virotherapy.
Some of these strategies have reached early clinical development with diverse little success.
CITATION Ann Hepatol. 2007 Jan-Mar;6(1):5-14