Extra-abdominal desmoid tumors. Diagnostic-therapeutic considerations and review of the literature
Barrios R.H., Leyes M., Losada J.I., Schweitzer D., Amillo S.
Departamento de Cirugía Ortopédica y Traumatología, Clínica Universitaria, Facultad de Medicina, Universidad de Navarra.
The authors review the literature, discuss clinical aspects and options in the management of desmoid tumors, analyze recent advances in the understanding of its biology and how they affect therapeutic choices, and outline future treatment perspectives.
We conclude that although recurrence rates are high, wide excision is the best firs approach. If it is not possible, marginal surgery and radiation therapy can be performed. Radiation therapy can be also use in the attempt to control recurrent disease. Although many pharmacologic agents have been advocated there is no clear proof of their usefulness.
Systemic therapy may be considered for selected patients that are not amenable to local treatment.
CITATION Rev Med Univ Navarra. 1995 Jan-Mar;39(1):14-20