Scientific publications

Endovascular treatment of malignant superior vena cava syndrome secondary to lung cancer

Calsina Juscafresa L (1), Gil Bazo I (2), Grochowicz L (1), Páramo Alfaro M (3), López-Picazo González JM (2), Moreno Jiménez M (4), Bilbao Jaureguizar JI (3). (1a) Vascular Surgery , Clínica Universidad de Navarra , Pamplona , Spain.
(2b) Oncology , Clínica Universidad de Navarra , Pamplona , Spain.
(3c) Interventional Radiology , Clínica Universidad de Navarra , Pamplona , Spain.
(4d) Radiation Oncology , Clínica Universidad de Navarra , Pamplona , Spain.

Magazine: Hospital Practice

Date: Jun 26, 2017

Medical Oncology Radiology [SP] Vascular Surgery [SP] Radiation Oncology

OBJECTIVES:

Superior Vena Cava obstruction results in severe oedema of the upper thorax. Endovascular treatment allows a rapid restoration of the blood flow with a rapid resolution of symptoms. We retrospectively report a single institution's experience in stent placement for malignant Superior Vena Cava Syndrome (SVCS) caused by lung cancer.

METHODS:

Thirty-three consecutive patients (23 men, 10 women; median age, 57.6 years; range 34-71 years) who underwent endovascular SVCS palliative treatment were enrolled between August 2002 and June 2015. All patients presented SVCS secondary to lung cancer. Signs and symptoms of SVCS were scored.

RESULTS:

All procedures were successfully completed (100% technical success rate). Twenty-eight patients showed a progressive clinical improvement after endovascular treatment of SVCS (84.8% clinical success rate) within 48 hours, there were five clinical failures which improved progressively with posterior radiotherapy. During follow-up, three patients (9%) suffered intra or post-procedural complications (1 cardiac arrhythmia, 2 stent thrombosis).

CONCLUSIONS:

Stent placement in malignant SVCS seems to be an effective and rapid treatment for the relief of symptoms and quality of life improvement with a relatively low complications rate with a rapid resolution of symptoms. Therefore, it should be seriously considered as the first option in the SVC obstruction treatment.

CITATION  Hosp Pract (1995). 2017 Jun 26:1-6. doi: 10.1080/21548331.2017.1342507

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