Contraceptives and ischemic cardiopathy
García-Bolao I., Alegría E., Iglesias I., Velasco S., Alzamora P., Fidalgo M.L.
Departamento de Cardiología y Cirugía Cardiovascular, Facultad de Medicina, Universidad de Navarra, Pamplona.
Magazine: Revista de Medicina de la Universidad de Navarra
Date: Jul 1, 1990Cardiology
The incidence of myocardial infarction is higher in women that use oral contraceptives. The most important pathophysiologic mechanisms are:
- modification of coronary risk factors: the pill produces an elevation of both serum cholesterol and trygliceride levels, increase of blood pressure and decompensation of diabetes mellitus
- blood coagulation disorders: oral contraceptives increase platelet aggregation and fibrinogen blood levels, therefore they have a considerable thrombogenic capacity.
At this moment there are several update publications concerning this matter; however most of the mechanisms involved in the increase of coronary heart disease in this specific group still remain unclear.
CITATION Rev Med Univ Navarra. 1990 Jul-Sep;34(3):144-50
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