Scientific publications

How can we optimize the diagnostic and therapeutic approach to pneumonia? Expert opinion-based recommendations

Oct 1, 2024 | Magazine: Enfermedades Infecciosas y Microbiología Clínica

Mario Fernández-Ruiz  1 , Juan José Castón  2 , José Luis Del Pozo  3 , Jordi Carratalà  4 , Jesús Fortún  5 , Miguel Salavert  6 , Julián Torre-Cisneros  2 , José María Aguado  7 ; members of the OPENIN (Optimización de procesos clínicos para el diagnóstico y tratamiento de infecciones) Group; Ana Fernández Cruz  8 , Ana Ventura  9 , Belén Loeches  10 , Carlos Dueñas  11 , Cristina Tomás  12 , David Navarro  13 , Rosa Oltra  13 , Elena Resino-Foz  14 , Elisa García Vázquez  15 , Enrique Míguez  16 , Esperanza Merino  17 , Francisco Braojos  18 , Francisco Javier Martínez  19 , Francisco López-Medrano Pérez  20 , Isabel Machuca  21 , Javier Cobo  22 , Joaquín López Contreras  23 , José María Reguera  24 , Juan Diego Ruiz Mesa  24 , Juan Tiraboschi  25 , Lucy Abella  26 , Mar Masiá  27 , María Dolores Del Toro López  28 , María Dolores Díaz López  29 , Nerea Carrasco-Antón  30 , Nicolás Merchante  31 , Patricia Muñoz  32 , Rafael Torres  33 , Regino Rodríguez  34 , Tatiana Mata-Forte  35 , Vicente Abril  36


Abstract

Pneumonia continues to be one of the most frequent infectious syndromes and a relevant cause of death and health resources utilization. The OPENIN ("Optimización de procesos clínicos para el diagnóstico y tratamiento de infecciones") Group is composed of Infectious Diseases specialists and Microbiologists and aims at generating recommendations that can contribute to improve the approach to processes with high impact on the health system. Such task relies on a critical review of the available scientific evidence.

The first Group meeting (held in October 2023) aimed at answering the following questions: Can we optimize the syndromic and microbiological diagnosis of pneumonia? Is it feasible to safely shorten the length of antibiotic therapy? And, is there any role for the immunomodulatory strategies based on the adjuvant use of steroids, macrolides or immunoglobulins?

The present review summarizes the literature reviewed for that meeting and offers a series of expert recommendations.

CITATION  Enferm Infecc Microbiol Clin (Engl Ed). 2024 Oct;42(8):442-452. doi: 10.1016/j.eimce.2024.07.001