Scientific publications

Brief Report About the Role of Hyperthermic Intraperitoneal Chemotherapy in a Prospective Randomized Phase 3 Study in Recurrent Ovarian Cancer From Spiliotis et al.

Harter P (1), Reuss A, Sehouli J, Chiva L, du Bois A.
1*Department of Gynecology & Gynecologic Oncology, Kliniken Essen Mitte, Essen; †Coordinating Center for Clinical Trials, Philipps-University Marburg, Marburg; ‡Department of Gynecology, Charité, Berlin, Germany; and §Department of Gynecology Oncology, MD Anderson Cancer Center, Madrid, Spain.

Magazine: International Journal of Gynecological Cancer

Date: Feb 1, 2017

Control del embarazo y parto. Dar a luz. Clínica Universidad de Navarra [SP]

With great interest, we read the publication about the first published randomized trial regarding Hyperthermic intraperitoneal chemotherapy (HIPEC) ‘‘Cytoreductive Surgery and HIPEC in Recurrent Epithelial Ovarian Cancer: A Prospective Randomized Phase III Study’’ by Spiliotis et al published in Annals of Surgical Oncology.

The authors report a benefit regarding mean survival for the use of HIPEC in addition to cytoreductive surgery in patients with recurrent ovarian cancer.

This was the first randomized trial for this new treatment modality and has potential to change clinical practice. Therefore, thorough critical discussion is of clinical and scientific importance.

CITATION Int J Gynecol Cancer. 2017 Feb;27(2):246-247. doi: 10.1097/IGC.0000000000000864



The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra


The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.

Imagen profesionales de la Clínica Universidad de Navarra


Learn why we are different from other healthcare centers. Quality, speed, comfort and results.

Imagen del edificio de la Clínica Universidad de Navarra