Scientific publications

Angiostrongyliasis in a European patient: a rare cause of gangrenous ischemic enterocolitis

Vázquez JJ, Boils PL, Sola JJ, Carbonell F, de Juan Burgueño M, Giner V, Berenguer-Lapuerta J.
Department of Pathology, University Clinic and School of Medicine, University of Navarra, Pamplona, Spain.

Magazine: Gastroenterology

Date: Nov 1, 1993

Pathological Anatomy [SP]

Angiostrongylus costaricensis causes a clinicopathologic disease first observed in Costa Rica, mainly in children characterized by highly symptomatic eosinophilic gastroenteritis involving the terminal ileum, cecum, appendix, and ascending colon.

A case of angiostrongyliasis in an adult Spaniard infected during a brief stay in Nicaragua is reported. We examined the macro-microscopic features of a right ileocolic resection of a 52-year-old patient. In the surgical specimen, multiple confluent ulcers, some perforated, were observed particularly in the terminal ileum.

he intestinal wall was thickened, and the arterial branches presented necrotizing arteritis with thrombosis and a heavy infiltrate of eosinophils around the vessels. In addition, some granulomas were observed. Adult male and female forms of A. costaricensis were found in the lumen of many arterial branches and in the tissue of the omentum, surrounded by dense eosinophilic infiltrate.

A. costaricensis causes an intense eosinophilic, necrotizing arteritis associated with thrombosis leading to severe ischemic lesions. This is the first case to be diagnosed in Europe. Incubation time was able to be established within a period of at least 14 days.

CITATION  Gastroenterology. 1993 Nov;105(5):1544-9



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