Allergology and Immunology department

The Allergology and Immunology Department at the Clínica is part of the Global Allergy and Asthma European Network, made up of the 25 best Allergology departments in Europe, chosen for their scientific excellence, multidisciplinary work, teaching and international activities.

We have the most advanced diagnostic techniques, and are leaders in research, working alongside the best experts in the field. We also have over 50 years' experience of patient care.

We were the first Spanish centre to start using the microarray technique. This allows us to evaluate the patient's reactivity to molecular components in foods, pollens, insects, animals, latex, etc. in just one test.

This test activates the basophiles  so that it possible to diagnose allergies in vitro. It works well as a complementary test for cutaneous examinations and is a useful tool in deciding when to carry out drugs tolerance testing.

Furthermore, we offer innovative treatments with excellent results, like testing for chronic urticaria with antibodies, and the best patient care, with nurses who are specialised in these diseases.

El Departamento de Alergología de la Clínica Universidad de Navarra ha sido reconocido como el primer hospital privado con mayor reputación de España en la asistencia en Alergología.

The Allergology and Immunology Department at the Clínica has more than 50 years experience. We diagnose diseases with the latest scientific advances and treat all types of allergological diseases.”

We diagnose and treat all types of allergological diseases. Some of the most frequently diagnosed conditions include:

In the Allergology and Immunology Department at the Clínica Universidad de Navarra we treat, once diagnosed, all allergological diseases included in this area of speciality:

Allergological in vitro diagnostic techniques

When diagnosing a disease, it is extremely important to recommend the appropriate immunotherapy or pharmacological treatments and monitor a patient's progress throughout the course of their disease.

This entails identifying the causative agent for the clinical reaction, but it's not always possible to do so due to the antigen's characteristics, standardisation, sensitivity and the specificity of the techniques required.

Serological techniques

  • Calculating total IgE, specific IgE and the antigen's specific IgG4
  • Tryptase calculation
  • Atopy test
  • Eosinophil cationic protein
  • Precipitins

Cell trials

In these tests, the patient's in vitro cells are stimulated with the allergen believed to provoke allergic reactions. Then, the specialists use flow cytometry with the histamine or sulfidoleucotrienos that the cells produce when an immediate allergic reaction occurs. They also analyse the reaction markers of the activated effector cells (basophiles).

Basophiles activation tests

This is a new and very useful procedure in the diagnosis of allergic reactions to different allergens, especially immediate reactions, like drugs: antibiotics, analgesics, anaesthetics, etc.

The test detects the reaction markers of the activated effector cells connected to fluorochromes through flow cytometry, allowing the specialists to confirm the diagnosis and decide what tolerance tests to use.

Molecular diagnosis of allergies

This is carried out using microarrays and compliments cutaneous testing and other in vitro diagnostic techniques. A 5x5 mm microchip is fixed to 103 molecular components.

The microchip is fixed to the components after the surface has been bathed in specific IgE antibodies from the patient ́s blood

After this, the components detected precisely reveal the patient's sensitivity.



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Estudio para investigar la eficacia y seguridad de ligelizumab (QGE031) en el tratamiento de la urticaria crónica espontánea (UCE) en adolescentes y adultos inadecuadamente controlados

El propósito de este estudio es evaluar la eficacia y seguridad de ligelizumab durante el tratamiento de pacientes adultos y adolescentes con urticaria crónica espontánea

Imagen Inmaculada, paciente con urticaria crónica

Although there is still no cure, with the medication they recommended me, I now have a completely normal quality of life.” 

Inmaculada G.

A patient treated for chronic urticaria

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