Dr. Mª José Cuadrado Lozano
Preferential dedication to systemic autoimmune diseases (Lupus erythematosus, antiphospholipid syndrome) and pregnancy in patients with rheumatic diseases.
Graduated in Medicine and Surgery from the University of Malaga, 1979.
MIR in Rheumatology at the Hospital "Carlos Haya" Malaga, 1982-1986.
Medical Specialist in the Rheumatology Service, Hospital Reina Sofia de Cordoba, 1987-1997.
Doctor of Medicine in 1990 by the University of Cordoba.
Research stay at the Lupus Unit, St. Thomas Hospital (London), 1993-1994.
Senior Research Fellow, Lupus Unit, St. Thomas' Hospital, London 1998-2000.
Arthritis Research Campaign (ARC) Fellow, Lupus Research Unit, St. Thomas' Hospital (London), 2000-2005.
Consultant Rheumatologist, Lupus Unit and Rheumatology Department, Guys and St Thomas' Hospital, London. 2003-2018.
Fellow Royal College of Physician, London, 2006-until now.
Her main areas of research are:
- Clinical and treatment aspects of systemic lupus erythematosus
- Mechanisms of Thrombosis and Treatment of Anti-Phospholipid Syndrome
- Clinical and treatment aspects in pregnancy of systemic autoimmune diseases
This interest is reflected in the research projects she has worked on, supported by public or private funding, and in her publications.
1991: Principal Investigator: De Ramon E,Co-solicitors: Camps MT, Cuadrado MJ, Nebro A. "Immunogenetic aspects of connective tissue disease and its relationship to antibody synthesis and clinical events".
1992: Principal Investigator: MJ Square, "Systemic lupus erythematosus and antiphospholipid syndrome: clinical and therapeutic aspects". (St. Thomas' Hospital, London, United Kingdom).
1993: Principal Investigator: De Ramon E,Co-applicators: Camps MT, Cuadrado MJ, Nebro A. "Systemic lupus erythematosus: Results and survival".
1995: Principal Investigator: MJ Square. Co-applicants: de Ramon E, Camps MT, Tinahones F, Khamashta MA, Hughes GRV "b2-glycoprotein I in Systemic lupus erythematosus and Antiphospholipid syndrome: Correlation with clinical events".
1997: Principal Investigator: MJ Square. Co-applicants: Camps MT, Tinahones F, Aguirre MA, Khamashta MA, Hughes GRV Tissue factor pathway in primary antiphospholipid.
2000-2006: Principal Investigator: Khamashta MA. Coordinator: MJ Square "Prospective, multicenter, randomized trial comparing low-dose aspirin with low-dose aspirin plus low-intensity oral anticoagulation in the primary prevention of thrombosis in antiphospholipid antibody positive patients".
2001-2003: Expression of NfkappaB transcription factors and its inhibitor IkappaB in patients with antiphospholipid syndrome.
2003-2006 Molecular expression of tissue factor in monocytes of patients with antiphospholipid syndrome: role of statins as antithrombotic therapy.
2007-2010 Effect of statins and antioxidants on cellular and molecular mechanisms in patients with PSA and SLE.
2007-2010 Immunogenetic susceptibility and metabolic alterations as etiopathogenic factors of chronic pain in patients with Sjogren's syndrome compared to primary care patients.
2009-2011: Mitochondrial dysfunction and oxidative stress in atherothrombosis associated with systemic autoimmune diseases. Genomic and proteomic analysis.
2011-2014: New oral anticoagulants for the treatment of patients with thrombotic antiphospholipid syndrome: a prospective randomized controlled trial of warfarin versus rivaroxaban. Arthritis Research UK. Co-investigator.
AREAS OF INTEREST
- Systemic Lupus Erythematosus
- Antiphospholipid syndrome
- Pregnancy monitoring in women with autoimmune diseases
As an educator
Associate Professor at the University of Cordoba (1990-1997).
Senior Lecture in Rheumatology, Kings College University (London).
Regular invited speaker at national and international congresses/symposiums, in the area of systemic autoimmune diseases.
During 2017 she was invited as a speaker at 18 congresses/symposia.
As a researcher
She has published 108 scientific articles in indexed journals (See: PUBMED, Cuadrado MJ)
She is the co-author of more than 50 chapters of books in her specialty.
In the last two years she has presented more than 15 papers in national and international congresses of her specialty.
- Spanish Society of Rheumatology.
- British Society of Rheumatology.
- American College of Rheumatology.
Latest scientific publications
- EULAR recommendations for the management of antiphospholipid syndrome in adults Oct 1, 2019 | Magazine: Annals of the Rheumatic Disease
- Can we treat systemic lupus erythematosus and other autoimmune diseases without oral steroids? Oct 17, 2018 | Magazine: Expert Review of Clinical Immunology