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Clinical trial of THOR-707 dosing in monotherapy and as combination therapy in adult subjects with advanced or metastatic solid tumors.

THE PRIMARY OBJECTIVE IS TO ASSESS THE SAFETY AND TOLERABILITY OF THOR-707 IN MONOTHERAPY AND AS COMBINATION THERAPY (IDENTIFY TLD [EXCEPT COHORTS H, E AND F], AA PROFILE/SERIOUS ADVERSE EVENTS) (EXCEPT COHORT H) ¿ DEFINE THE TLD AND/OR DRF2 OF THOR-707 IN MONOTHERAPY AND AS COMBINATION THERAPY (FOR PART 1 AND PART 2 ONLY). ¿ EVALUATE THE PRELIMINARY ANTITUMOR ACTIVITY OF THOR-707 IN MONOTHERAPY BY DETERMINING THE OBJECTIVE RESPONSE RATE (ORR) DEFINED ACCORDING TO THE RESPONSE EVALUATION CRITERIA IN SOLID TUMORS (RECIST), VERSION 1.1 (COHORT H ONLY).

Status
In recruitment
headquarters
Madrid

Technical Summary

* The trials only admit a limited number of patients and are subject to inclusion and exclusion criteria. The specialist who assesses your case will inform you of the conditions required to participate in the clinical trial.

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