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Clinical trial of the genetic vaccine Nous-209 for the treatment of solid tumors with microsatellite instability.
THE OBJECTIVE OF THIS CLINICAL RESEARCH STUDY IS TO EVALUATE THE SAFETY, TOLERABILITY, IMMUNE RESPONSE AND PRELIMINARY EVIDENCE OF ANTITUMOR ACTIVITY OF THE POLYVALENT GENETIC VACCINE NOUS-209 (GAD20-209-FSP PREPARATION AND MVA-209-FSP BOOSTER) AND PEMBROLIZUMAB. PEMBROLIZUMAB IS AUTHORIZED BY THE US FOOD AND DRUG ADMINISTRATION (FDA) AND THE EUROPEAN MEDICINES AGENCY (EMA) UNDER THE TRADE NAME KEYTRUDA®.
Technical Summary
- Code EudraCT: 2021-002823-40
- Protocol number: NOUS-209-01
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