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Clinical trial with ceralasertib monotherapy and ceralasertib plus durvalumab in patients with unresectable or advanced melanoma with primary or secondary resistance to PD-(L)1 inhibition.
THE AIM OF THIS STUDY IS TO TEST WHETHER CERALASERTIB MONOTHERAPY AND THE COMBINATION OF CERALASERTIB AND DURVALUMAB ARE SAFE AND EFFECTIVE IN THE TREATMENT OF PATIENTS WITH UNRESECTABLE OR ADVANCED MELANOMA, AND ALSO TO BETTER UNDERSTAND THE DISEASE AND ITS HEALTH PROBLEMS.
Technical Summary
- PHASE 2, RANDOMIZED, OPEN-LABEL STUDY OF CERALASERTIB MONOTHERAPY AND CELARALASERTIB PLUS DURVALUMAB IN PATIENTS WITH UNRESECTABLE OR ADVANCED MELANOMA AND WITH PRIMARY OR SECONDARY RESISTANCE TO PD-(L)1 INHIBITION. IMMUNOTHERAPY.
- Code EudraCT: 2021-001722-21
- Protocol number: D533AC00001
- Promoter: Astra Zeneca AB
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