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Clinical trial to determine the preliminary efficacy of CC-220 in monotherapy and in combination with dexamethasone in subjects with relapsed and refractory multiple myeloma.
THE PURPOSE OF THIS STUDY IS TO TEST THE SAFETY, AND ALSO TO TRY TO DEFINE THE APPROPRIATE DOSE OF AN INVESTIGATIONAL DRUG AND AN INVESTIGATIONAL DRUG COMBINATION. INVESTIGATIONAL MEANS THAT THE DRUG OR DRUG COMBINATION IS STILL BEING STUDIED AND THE RESEARCH DOCTORS ARE TRYING TO LEARN MORE ABOUT IT. IT ALSO MEANS THAT THE U.S. FOOD AND DRUG ADMINISTRATION (FDA) OR SOME HEALTH AUTHORITY HAS NOT CLEARED CC-220 OR THE COMBINATION OF CC-220 WITH DEXAMETHASONE FOR USE IN PATIENTS.
Technical Summary
- PHASE IB/IIA OPEN-LABEL, DOSE-ESCALATION, MULTICENTER STUDY TO DETERMINE THE MAXIMUM TOLERATED DOSE AND TO EVALUATE THE SAFETY AND TOLERABILITY, PHARMACOKINETICS AND PRELIMINARY EFFICACY OF CC-220 IN MONOTHERAPY AND IN COMBINATION WITH DEXAMETHASONE IN SUBJECTS WITH RELAPSED AND REFRACTORY MULTIPLE MYELOMA
- Code EudraCT: 2016-000860-40
- Protocol number: CC-220-MM-001
- Promoter: Celgene Corporation
- Molecule/Drug: CC-220
* The trials only admit a limited number of patients and are subject to inclusion and exclusion criteria. The specialist who assesses your case will inform you of the conditions required to participate in the clinical trial.
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