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Clinical trial of botensilimab (AGEN1181) in monotherapy and in combination with balstilimab (AGEN2034) or with investigator's choice of reference therapy (regorafenib or trifluridine and tipiracil) for the treatment of metastatic colorectal cancer.
THE GOAL OF THIS STUDY IS TO LEARN WHETHER A NEW TYPE OF IMMUNE-BASED TREATMENT CALLED BOTENSILIMAB (ALSO KNOWN AS AGEN1181), ALONE OR TOGETHER WITH BALSTILIMAB (ALSO KNOWN AS AGEN2034), CAN HELP PATIENTS WITH RCC WITHOUT IMS-A/DMMR.
- PHASE II, RANDOMIZED, UNBLINDED, PHASE II STUDY OF BOTENSILIMAB (AGEN1181) IN MONOTHERAPY AND IN COMBINATION WITH BALSTILIMAB (AGEN2034) OR WITH INVESTIGATOR'S CHOICE OF REFERENCE THERAPY (REGORAFENIB OR TRIFLURIDINE AND TIPIRACIL) FOR THE TREATMENT OF REFRACTORY METASTATIC COLORECTAL CANCER. IMMUNOTHERAPY
- Code EudraCT: 2022-502065-23
- Protocol number: C-800-25
- Promoter: Agenus Inc.
- Link to Clinical Trials
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