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Clinical trial of the pd-l1 inhibitor atezolizumab (mpdl3280a) administered with stereotactic ablative radiotherapy (sabr) in patients with metastatic tumors. immunotherapy.

THE AIM OF THE STUDY IS TO EVALUATE WHETHER A MORE EFFECTIVE AND PRECISE RADIOTHERAPY CALLED "STEREOTACTIC RADIOTHERAPY" COMBINED WITH IMMUNOTHERAPY WITH A PD-L1 INHIBITOR IS MORE EFFECTIVE IN TREATING METASTASES. THE PRIMARY OBJECTIVE OF THE PRESENT STUDY IS TO ANALYZE THE EFFICACY OF STEREOTACTIC RADIOTHERAPY COMBINED WITH IMMUNOTHERAPY WITH A PD-L1 INHIBITOR IN CONTROLLING THE DISEASE ONE YEAR AFTER THE APPEARANCE OF THE METASTASIS(S). THE SECONDARY OBJECTIVE OF THIS STUDY IS TO TEST THE TOXICITY OF THESE TREATMENTS.

Status
In recruitment
headquarters
Pamplona

Technical Summary

  • PHASE II STUDY TO EVALUATE THE EFFICACY OF THE PD-L1 INHIBITOR, ATEZOLIZUMAB (MPDL3280A), ADMINISTERED WITH STEREOTACTIC ABLATIVE RADIOTHERAPY (SABR) IN PATIENTS WITH METASTATIC TUMORS. IMMUNOTHERAPY.
  • Code EudraCT: 2015-005464-42
  • Protocol number: SABR/PDL1
  • Promoter: Gustave Roussy
  • Molecule/Drug: Atezolizumab
  • Link to Clinical Trials

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