Publicações científicas

The influence of gender and atopy in the relationship between obesity and asthma in childhood

Alvarez Zallo N (1), Aguinaga-Ontoso I (2), Alvarez-Alvarez I (2), Guillén-Grima  F (3), Azcona San Julian C (4).
(1) Extrahospitalary Pediatric Emergency Service, Osasunbidea, Pamplona, Navarra, Spain.
(2) Department of Health Sciences, Public University of Navarra, Spain.
(3) Department of Health Sciences, Public University of Navarra, Spain; Preventive Medicine, Clínica Universidad de Navarra, Pamplona, Navarra, Spain; Navarra Institute for Health Research (IdiSNA), Spain.
(4) Navarra Institute for Health Research (IdiSNA), Spain; Paediatric Endocrinology Unit, Department of Pediatrics, Clínica Universidad de Navarra, Pamplona, Navarra, Spain. 

Revisão:Allergologia et Immunopathologia

Data: 23/Jan/2017

Pediatria [ES] Medicina Preventiva [ES]

BACKGROUND:
The objective of the study was to examine the relationship between asthma and overweight-obesity in Spanish children and adolescents and to determine whether this relationship was affected by gender and atopy.

METHODS:
The study involves 8607 Spanish children and adolescents from the International Study of Asthma and Allergies in Childhood phase III. Unconditional logistic regression was used to obtain adjusted odds ratios (OR) and 95% confidence intervals (95% CI) for the association between asthma symptoms and overweight-obesity in the two groups. Afterwards, it was stratified by sex and rhinoconjunctivitis.

RESULTS:
The prevalence of overweight and obesity in 6-7-year-old children was 18.6% and 5.2% respectively and in 13-14 year-old teenagers was 11.4% and 1.1% respectively.

Only the obese children, not the overweight children, of the 6-7 year old group had a higher risk of any asthma symptoms (wheezing ever: OR 1.68 [1.15-2.47], asthma ever: OR 2.29 [1.43-3.68], current asthma 2.56 [1.54-4.28], severe asthma 3.18 [1.50-6.73], exercise-induced asthma 2.71 [1.45-5.05]). The obese girls had an increased risk of suffering any asthma symptoms (wheezing ever: OR 1.73 [1.05-2.91], asthma ever: OR 3.12 [1.67-5.82], current asthma 3.20 [1.65-6.19], severe asthma 4.83[1.94-12.04], exercise-induced asthma 3.68 [1.67-8.08]). The obese children without rhinoconjunctivitis had a higher risk of asthma symptoms.

CONCLUSIONS:
Obesity and asthma symptoms were associated in 6-7 year-old children but not in 13-14 year-old teenagers. The association was stronger in non-atopic children and obese girls.

CITAÇÃO DO ARTIGO  Allergol Immunopathol (Madr). 2017 Jan 23. pii: S0301-0546(16)30155-0. doi: 10.1016/j.aller.2016.09.005

talvezlhe interesse

QUE TECNOLOGIA UTILIZAMOS? 

A Clínica é o hospital privado com maiores recursos tecnológicos de Espanha, tudo num único centro.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra

OS NOSSOS
PROFISSIONAIS

Os profissionais da Clínica realizam um trabalho contínuo de investigação e formação, sempre em benefício do paciente.

Imagen profesionales de la Clínica Universidad de Navarra

RAZÕES PARA VIR
À CLÍNICA

Conheça porque é que somos diferentes em relação a outros centros sanitários. Qualidade, rapidez, comodidade e resultados.

Imagen del edificio de la Clínica Universidad de Navarra