Scientific publications

Severe colon ischemia in patients with severe coronavirus-19 (COVID-19). Scientific Publication

Sep 21, 2020 | Magazine: Revista Española de Enfermedades Digestivas

Ana Almeida Vargas 1 , Víctor Valentí 2 , Carlos Sánchez Justicia 2 , Fernando Martínez Regueira 2 , Pablo Martí Cruchaga 2 , Juan Luján Colás 2 , Daniel Aliseda Jover 2 , Sara Esteban Gordillo 2 , Javier A Cienfuegos 3 , Fernando Rotellar Sastre 2


Abstract

COVID-19 is associated with severe coagulopathy. We present three cases of colonic ischemia that can be attributed to the hypercoagulable state related with SARS-CoV2 and disseminated intravascular coagulation.

Three males aged 76, 68 and 56 with respiratory distress presented episodes of rectal bleeding, abdominal distension and signs of peritoneal irritation.

Endoscopy (case 1) and computed tomography angiography revealed colonic ischemia. One patient (case 2) in which a computed tomography (CT) scan showed perforation of the gangrenous cecum underwent surgery. D-dimer levels were markedly increased (2,170, 2,100 and 7,360 ng/ml) in all three patients. All three patients died shortly after diagnosis.

CITATION   Rev Esp Enferm Dig. 2020 Sep 21;112. doi: 10.17235/reed.2020.7329/2020