Scientific publications

Response Assessment in Neuro-Oncology working group and European Association for Neuro-Oncology recommendations for the clinical use of PET imaging in gliomas

Apr 21, 2016 | Magazine: Neuro-Oncology

Albert NL (1), Weller M (1), Suchorska B (1), Galldiks N (1), Soffietti R (1), Kim MM (1), la Fougère C (1), Pope W (1), Law I (1), Arbizu J (1), Chamberlain MC (1), Vogelbaum M (1), Ellingson BM (1), Tonn JC (2).

This guideline provides recommendations for the use of PET imaging in gliomas. The review examines established clinical benefit in glioma patients of PET using glucose ((18)F-FDG) and amino acid tracers ((11)C-MET, (18)F-FET, and (18)F-FDOPA).

An increasing number of studies have been published on PET imaging in the setting of diagnosis, biopsy, and resection as well radiotherapy planning, treatment monitoring, and response assessment. Recommendations are based on evidence generated from studies which validated PET findings by histology or clinical course.

This guideline emphasizes the clinical value of PET imaging with superiority of amino acid PET over glucose PET and provides a framework for the use of PET to assist in the management of patients with gliomas.

CITATION  Neuro Oncol. 2016 Sep;18(9):1199-208. doi: 10.1093/neuonc/now058. Epub 2016 Apr 21