Scientific publications

Intracavitary and systemic daptomycin for successful treatment of a postpneumonectomy intrathoracic infection

Sangro P (1), Carmona-Torre F (1,2), Mesa M (3), Del Pozo JL (2,4), Yuste JR (5,2). (1) Department of Internal Medicine, Clínica Universidad de Navarra, Pamplona, Spain.
(2) Division of Infectious Diseases, Clínica Universidad de Navarra, Pamplona, Spain.
(3) Department of Thoracic Surgery. Clínica Universidad de Navarra, Pamplona, Spain.
(4) Department of Clinical Microbiology, Clínica Universidad de Navarra, Pamplona, Spain.
(5) Department of Internal Medicine, Clínica Universidad de Navarra, Pamplona, Spain.

Magazine: Antimicrobial Agents Chemotherapy

Date: Aug 28, 2017

Internal Medicine [SP] Infectious Diseases [SP] Thoracic Surgery

ABSTRACT

Treatment of an infected postneumonectomy cavity is very difficult.

We present a patient with an infection of a postneumonectomy cavity by Staphylococcus epidermidis treated with local daptomycin for different dwell times, maintaining high antibiotic levels over minimum inhibitory concentration. Clinical and microbiological cure were achieved successfully.

CITATION  Antimicrob Agents Chemother. 2017 Aug 28. pii: AAC.01330-17. doi: 10.1128/AAC.01330-17

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