Scientific publications
Flow Cytometry
Gascue A (1), Merino J (1), Paiva B (2)
(1) Department of immunology, Clínica Universidad de Navarra, Av. Pio XII, 36, Pamplona, 31008, Spain.
(2) Department of immunology, Clínica Universidad de Navarra, Av. Pio XII, 36, Pamplona, 31008, Spain; Centre for Applied Medical Research (CIMA), Pamplona, Spain; Healthcare Research Institute of Navarre (IDISNA), Pamplona, Spain; CIBERONC, Spain.
Magazine: Hematology/Oncology Clinics of North America
Date: Oct 1, 2018
Immunology [SP]ABSTRACT
Multiparameter flow cytometry (MFC) is valuable in the diagnosis and monitoring of most hematological malignancies.
Although the assessment of cellular infiltrates in Waldenström macroglobulinemia (WM) relies on morphology and immunohistochemistry grounds, there is evidence pointing to the clinical significance of MFC in this disease.
Herein, the authors review immunophenotypic patterns of B-cell development, the antigen profile of the WM clone and its normal B-cell counterpart, the clinical applicability of MFC in the differential diagnosis of immunoglobulin M-secreting lymphoproliferative disorders and monoclonal gammopathies, and its potential role in detecting minimal residual disease and monitoring treatment efficacy in WM.
CITATION Hematol Oncol Clin North Am. 2018 Oct;32(5):765-775. doi: 10.1016/j.hoc.2018.05.004
you mayBE INTERESTED
WHAT TECHNOLOGY
DO WE USE?
The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.
OUR
PROFESSIONALS
The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.
WHY CHOOSE
THE CLINICA?
Learn why we are different from other healthcare centers. Quality, speed, comfort and results.
