Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
F Cardoso 1 , S Kyriakides 2 , S Ohno 3 , F Penault-Llorca 4 5 , P Poortmans 6 7 , I T Rubio 8 , S Zackrisson 9 , E Senkus 10 , ESMO Guidelines Committee.
Incidence and epidemiology
In 2018, the predicted number of new breast cancers in 28 European Union (EU) countries was 404 920, with estimated age-adjusted annual incidence of breast cancer of 144.9/100 000 and mortality of 32.9/100 000, with 98 755 predicted deaths .
Worldwide, there was about 2.1 million newly diagnosed female breast cancer cases in 2018, accounting for almost one in four cancer cases among women, and ∼630 000 died of it . Breast cancer incidence has increased since the introduction of mammography screening and continues to grow with the ageing of the population...