Cytogenetic marker del(12p) in a case of acute myeloid leukemia M4 with eosinophilia and inv(16)
Cigudosa JC, Calasanz MJ, Gullón A, Cuesta B, Rifón J, Rocha E.
Departamento de Genética, Universidad de Navarra, Clínica Universitaria, Pamplona.
Date: Apr 1, 1992Hematología y Hemoterapia [SP]
A 35-year-old Spanish female having acute myelomonocytic leukaemia with marrow eosinophilia is reported. The karyotype revealed the specific chromosomal abnormality associated with this disorder, inv(16), and a less-specific myelodysplastic cytogenetic marker, del(12p).
We have reviewed the published cases in order to elucidate the possible significance of presenting a 12p deletion (nonrandomly associated with chronic myelomonocytic leukaemia) together with other chromosomal rearrangements.
CITATION Sangre (Barc). 1992 Apr;37(2):125-7
you mayBE INTERESTED
The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.
The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.
Learn why we are different from other healthcare centers. Quality, speed, comfort and results.