Cancer-Associated Thrombosis: Beyond Clinical Practice Guidelines-A Multidisciplinary (SEMI-SEOM-SETH) Expert Consensus
Pachón V (1), Trujillo-Santos J (2), Domènech P (3), Gallardo E (4), Font C (5), González-Porras JR (6), Pérez-Segura P (7), Maestre A (8), Mateo J (9), Muñoz A (10), Peris ML (11), Lecumberri R (12).
(1) Department of Oncology, Hospital Universitario Ramón y Cajal, Madrid, Spain.
(2) Department of Internal Medicine, Hospital Universitario Santa Lucía, Cartagena, Spain.
(3) Thrombosis and Haemostasis Unit, Hospital Universitario Bellvitge, L'Hospitalet de Llobregat, Catalonia, Spain.
(4) Department of Oncology, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell, Spain.
(5) Department of Medical Oncology, Hospital Clinic, Barcelona, Spain.
(6) Hematology Service, Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain.
(7) Department of Oncology, Hospital Clínico San Carlos, Madrid, Spain.
(8) Department of Internal Medicine, Hospital del Vinalopó, Elche, Spain.
(9) Hematology Service, Hospital Santa Creu i Sant Pau, Barcelona, Spain.
(10) Department of Oncology, Hospital Universitario Gregorio Marañón, Madrid, Spain.
(11) Department of Internal Medicine, Hospital Provincial de Castellón, Castellón, Spain.
(12) Hematology Service, Clínica Universidad de Navarra, IDISNA, CIBER-CV, Pamplona, Spain.
Despite the growing interest and improved knowledge about venous thromboembolism in cancer patients in the last years, there are still many unsolved issues.
Due to the limitations of the available literature, evidence-based clinical practice guidelines are not able to give solid recommendations for challenging scenarios often present in the setting of cancer-associated thrombosis (CAT).
A multidisciplinary expert panel from three scientific societies-Spanish Society of Internal Medicine (SEMI), Spanish Society of Medical Oncology (SEOM), and Spanish Society Thrombosis and Haemostasis (SETH)-agreed on 12 controversial questions regarding prevention and management of CAT, which were thoroughly reviewed to provide further guidance.
The suggestions presented herein may facilitate clinical decisions in specific complex circumstances, until these can be made leaning on reliable scientific evidence.
CITATION TH Open. 2018 Nov 5;2(4):e373-e386. doi: 10.1055/s-0038-1675577