CA-125 levels in predicting optimal cytoreductive surgery in patients with advanced epithelial ovarian carcinoma
Alcázar JL, Miranda D, Unanue A, Novoa E, Alemán S, Madariaga L.
Department of Obstetrics and Gynecology, Clínica Universitaria de Navarra, School of Medicine, University of Navarra, Pamplona, Spain.
Magazine: International Journal of Gynaecology and Obstetrics
Date: Feb 1, 2004Gynaecology and Obstetrics [SP]
Primary cytoreductive surgery is considered as one of the cornerstones in the management of patients with advanced ovarian cancer. Recently, the CA-125 serum marker has been proposed for predicting optimal cytoreduction in advanced epithelial ovarian cancer.
In this study we assessed the role of preoperative CA-125 to predict optimal cytoreduction in patients with advanced ovarian cancer. Data on patients 67 patients (mean age: 57 years old, range 21–85 years) with advanced epithelial ovarian cancer that underwent primary cytoreduction surgery at our institution were reviewed. Optimal cytoreduction was defined as the largest volume tumoral residual disease of less than 1 cm. Optimal cytoreduction was achieved in 32 patients.
CITATION Int J Gynaecol Obstet. 2004 Feb;84(2):173-4
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