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Phase II clinical trial evaluating the safety and efficacy of repotrectinib in patients with ROS1-positive non-small cell lung cancer with active brain metastases.
THE PRIMARY OBJECTIVE OF THIS STUDY IS TO EVALUATE THE EFFICACY OF THE STUDY DRUG REPOTRECTINIB (A KINASE INHIBITOR THAT BLOCKS THE ACTIVITY OF THE ABNORMAL ROS1 PROTEIN) IN PATIENTS WITH NSCLC WHO HAVE A ROS1 ALTERATION AND ACTIVE BRAIN METASTASES.
Technical Summary
- PHASE II STUDY EVALUATING THE SAFETY AND EFFICACY OF REPOTRECTINIB IN PATIENTS WITH ROS1-POSITIVE NON-SMALL CELL LUNG CANCER WITH ACTIVE BRAIN METASTASES (REPOSE STUDY).
- Code EudraCT: 2023-508112-35-00
- Protocol number: MEDOPP662
- Promoter: Medica Scientia Innovation Research SL
- Molecule/Drug: Repotrectinib
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