Clinical trials
for patients
Learn about available clinical trials
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May 27, 2026Pamplona/MadridIn recruitment
GCT1184-03 Phase III clinical trial of rinatabart sesutecan (Rina-S) compared with investigator’s choice of treatment in patients with endometrial cancer following platinum-based chemotherapy and PD(L)-1 therapy
The primary objective is to compare the clinical efficacy of Rina-S with the investigator’s choice (IC) of treatment in patients with recurrent or progressive endometrial cancer (EC) following prior treatment. -
May 25, 2026MadridIn recruitment
MK-2870-021 Clinical trial of sacituzumab timurotecan (sac-TMT, MK-2870) as maintenance therapy in participants with advanced ovarian cancer
The primary objective is to compare sac-TMT maintenance therapy with or without bevacizumab against standard of care (SoC) in terms of PFS as defined by RECIST 1.1, as assessed by the BICR. -
May 25, 2026PamplonaIn recruitmentEarly phase
MCLA-158-CL04 A Phase 2 Study of Petosemtamab in Combination with Docetaxel as Second-Line or Pembrolizumab as First-Line Metastatic Treatment in Adults with NSCLC.
You are invited to participate in this study because you have metastatic lung cancer. To participate in this study, your lung cancer must express a protein called programmed death-ligand 1 (PD-L1). PD-L1 is a protein found on cancer cells that can prevent the body’s immune system from attacking the cancer cells. Pembrolizumab is a treatment that blocks the effects of PD-L1 and allows the immune system to attack and kill cancer cells. Your disease must have a PD-L1 score of ≥50%. This re... -
May 25, 2026Pamplona/MadridIn recruitment
8951-CL-0305 A study of zolbetuximab in combination with pembrolizumab and chemotherapy in adults with gastric cancer (LUCERNA).
The aim of this research study is to test a new treatment for a specific type of stomach cancer. It is intended for people whose cancer cells express certain proteins (claudin 18.2 and PD-L1) and do not express another protein called HER2 -
May 20, 2026PamplonaIn recruitmentEarly phase
D798VC00001 Clinical trial to evaluate the safety and efficacy of new interventions and treatment combinations in participants with colorectal cancer
The purpose of this study is to learn more about the effectiveness and safety of the study drug, volrustomig (also known as MEDI5752), when given in combination with a standard treatment for colorectal cancer. -
May 19, 2026PamplonaIn recruitmentEarly phase
2012-0001 A clinical trial in people with advanced cancer to investigate the tolerability of different doses of BI 3819026 when taken alone and in combination with ezabenlimab.
The purpose of this study is to determine the highest dose of BI 3819026 that people with advanced cancer can tolerate when taken alone and in combination with ezabenlimab. -
May 19, 2026Pamplona/MadridIn recruitmentEarly phase
GCT1079-01 A clinical trial to evaluate the safety and preliminary efficacy of GEN1079 in participants with certain advanced solid tumors.
The trial consists of 3 parts. The objective of Part 1 is to assess the safety of GEN1079 at increasing doses and to identify the doses to be used in subsequent phases. The objective of Part 2 is to refine and identify the dose that is effective while causing the fewest side effects. The goal of Part 3 is to further investigate whether GEN1079 works against the tumor and how it does so, and to continue learning about its side effects. -
May 19, 2026Pamplona/MadridIn recruitmentEarly phase
GCT1184-05 A study to evaluate the efficacy and safety of Rina-S in participants with non-small cell lung cancer.
The goal is to continuously monitor your well-being and safety, and to ask you if you have started a new treatment. If, for any reason, the doctor or trial staff are unable to contact you, a family member may provide information about your condition, or the trial doctor may obtain it from sources such as your medical records, national or local registries, or publicly available information, as permitted by local regulations. -
May 13, 2026Pamplona/MadridIn recruitment
42756493BLC3004 Clinical trial to evaluate the efficacy and safety of the TAR-210 erdafitinib intravesical delivery system compared with intravesical chemotherapy as monotherapy in patients with non-muscle-invasive bladder cancer
The main objective of this study is to compare disease-free survival (DFS) between patients receiving TAR-210 and investigator-selected intravesical chemotherapy. -
May 13, 2026Pamplona/MadridIn recruitmentEarly phase
IMC-P115C-1005 Phase I clinical trial of IMC-P115C in participants with PRAME-positive advanced cancers.
The main objective is to evaluate the safety and tolerability of IMC-P115C as monotherapy and in combination in participants with PRAME-positive advanced tumors, and to identify the MTD (maximum tolerated dose) and dosing regimens (combination of IMC-P115C dose, dosing frequency, and premedication) for further optimization.