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Clinical trial with E7386 in combination with Pembrolizumab in previously treated patients with specific solid tumors.
PRIMARY OBJECTIVE: PHASE IB PART: - TO EVALUATE THE SAFETY AND TOLERABILITY OF E7386 IN COMBINATION WITH PEMBROLIZUMAB IN PREVIOUSLY TREATED PATIENTS WITH SPECIFIC SOLID TUMORS - TO DETERMINE THE RECOMMENDED DOSE FOR PHASE 2 (DRF2) OF E7386 IN COMBINATION WITH PEMBROLIZUMAB PART PHASE 2: - TO EVALUATE THE OBJECTIVE RESPONSE RATE (ORR) OF E7386 IN COMBINATION WITH PEMBROLIZUMAB IN PREVIOUSLY TREATED PATIENTS WITH SPECIFIC SOLID TUMORS (MELANOMA, RCC, HCC).
Technical Summary
- OPEN-LABEL, MULTICENTER, PHASE 1B/2 STUDY WITH E7386 IN COMBINATION WITH PEMBROLIZUMAB IN PREVIOUSLY TREATED PATIENTS WITH SPECIFIC SOLID TUMORS. IMMUNOTHERAPY.
- Code EudraCT: 2021-001568-10
- Protocol number: E7386-G000-201
- Promoter: Eisai Inc.
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* The trials only admit a limited number of patients and are subject to inclusion and exclusion criteria. The specialist who assesses your case will inform you of the conditions required to participate in the clinical trial.
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