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T-cell trial, Talquetamab and Teclistamab, in subjects with relapsed or refractory multiple myeloma.
THE OBJECTIVE OF THIS STUDY IS TO FIND A SAFE AND TOLERABLE DOSE AND ADMINISTRATION SCHEDULE FOR THE COMBINED ADMINISTRATION OF 2 STUDY DRUGS, TALQUETAMAB (ALSO KNOWN AS JNJ-64407564) AND TECLISTAMAB (ALSO KNOWN AS JNJ-64007957). THIS STUDY DRUG COMBINATION WILL BE ADMINISTERED TO PATIENTS WITH MULTIPLE MYELOMA WHO HAVE EXPERIENCED PROGRESSION AFTER RECEIVING BASELINE OR LICENSED THERAPY. A DOSE IS THE AMOUNT OF A DRUG THAT CAN BE ADMINISTERED AT ONE TIME. A DOSING SCHEDULE IS THE FREQUENCY WITH WHICH A DRUG IS ADMINISTERED.
- PHASE 1 DOSE-ESCALATION TRIAL TO EVALUATE THE COMBINATION OF TWO BISPECIFIC T-CELL REDIRECTION ANTIBODIES, TALQUETAMAB AND TECLISTAMAB, IN SUBJECTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA. IMMUNOTHERAPY
- Code EudraCT: 2019-004124-38
- Protocol number: 64007957MMY1003
- Promoter: Janssen-Cilag
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