Get to know our clinical trials

Ensayo clínico para evaluar la seguridad y eficacia de ALXN1720 en adultos con miastenia gravis generalizada

THE PURPOSE OF THIS TRIAL IS TO LEARN MORE ABOUT AN INVESTIGATIONAL DRUG CALLED ALXN1720 AND TO BETTER UNDERSTAND MYASTHENIA GRAVIS, THE DISEASE BEING STUDIED, AS WELL AS ASSOCIATED HEALTH PROBLEMS. MYASTHENIA GRAVIS IS A CONDITION THAT CAUSES ABNORMALITIES IN THE IMMUNE SYSTEM THAT CAN LEAD TO GENERALIZED MUSCLE WEAKNESS, INCLUDING WEAKNESS IN CARRYING OUT EYE MOVEMENTS, DECREASED ABILITY TO SPEAK OR SWALLOW, AND DIFFICULTY BREATHING. THIS DISEASE CAN ALSO CAUSE FATIGUE, WHICH CAN MAKE DAILY ACTIVITIES DIFFICULT. THE IMMUNE SYSTEM HELPS OUR BODY FIGHT DISEASE. AN IMPORTANT PART OF THE IMMUNE SYSTEM IS A GROUP OF MOLECULES CALLED COMPLEMENT PROTEINS. ABNORMAL ACTIVATION OF THESE PROTEINS CAN CAUSE RARE DISEASES SUCH AS MGG. THE ROLE OF THE DRUG USED IN THIS TRIAL IS TO BLOCK THE ACTIVATION OF ONE OF THESE COMPLEMENT PROTEINS. THIS APPROACH TO TREATING MGG HAS WORKED WELL IN OTHER TRIALS WITH SIMILAR DRUGS. TO LEARN MORE ABOUT THE TRIAL DRUG, IT WILL BE COMPARED TO A PLACEBO. ULTIMATELY, THE PURPOSE OF THIS TRIAL IS TO DETERMINE WHETHER THE TRIAL DRUG IS SAFE AND EFFECTIVE IN TREATING MGG.

Status
In recruitment
headquarters
Pamplona

Technical Summary

  • PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL, MULTICENTER, DOUBLE-BLIND STUDY TO EVALUATE THE SAFETY AND EFFICACY OF ALXN1720 IN ADULTS WITH GENERALIZED MYASTHENIA GRAVIS
  • Code EudraCT: 2022-00460-21
  • Protocol number: ALXN1720-MG-301
  • Promoter: Alexion Pharmaceuticals, Inc.
  • Link to Clinical Trials

* The trials only admit a limited number of patients and are subject to inclusion and exclusion criteria. The specialist who assesses your case will inform you of the conditions required to participate in the clinical trial.

Do you want to participate in this trial?

Request an appointment for our specialists to assess whether you qualify for this clinical trial


Do you prefer to send us your reports?

If you prefer, you can send us your medical information and our specialists will evaluate your case without the need to come to the Clinica.