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Clinical trial of amivantamab and lazertinib with platinum-based chemotherapy in patients with advanced or metastatic EGFR-mutated non-small cell lung cancer (NSCLC) after osimertinib failure.
THE AIM OF THIS STUDY IS TO TEST WHETHER THE COMBINATION OF AMIVANTAMAB AND LAZERTINIB ADDED TO THE REFERENCE CHEMOTHERAPY (CARBOPLATIN AND PEMETREXED) IS SAFE AND USEFUL FOR THE TREATMENT OF PATIENTS WITH NSCLC, SPECIFICALLY, IN PATIENTS WITH A GENETIC ABNORMALITY CALLED EXON 19 DELETION OR EGFR EXON 21 L858R SUBSTITUTION, WHO HAVE RECEIVED PREVIOUS CANCER TREATMENT.
- RANDOMIZED, OPEN-LABEL, PHASE III STUDY OF THE COMBINED TREATMENT OF AMIVANTAMAB AND LAZERTINIB WITH PLATINUM-BASED CHEMOTHERAPY COMPARED TO PLATINUM-BASED CHEMOTHERAPY IN PATIENTS WITH ADVANCED OR METASTATIC EGFR-MUTATED NON-SMALL CELL LUNG CANCER (NSCLC) AFTER FAILURE OF OSIMERTINIB. IMMUNOTHERAPY
- Code EudraCT: 2021-001825-33
- Protocol number: 61186372NSC3002
- Promoter: Janssen Research & Development
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* The trials only admit a limited number of patients and are subject to inclusion and exclusion criteria. The specialist who assesses your case will inform you of the conditions required to participate in the clinical trial.
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Information offered by the Spanish Registry of Clinical Studies
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