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Clinical trial of AMG 160 in combination with abiraterone in subjects with metastatic castration-resistant prostate cancer (mCRPC)
THIS STUDY IS PERFORMED TO FURTHER INVESTIGATE AMG 160 IN COMBINATION WITH ABIRATERONE IN MEN WITH MCRPC. THE STUDY WILL CONSIST OF 2 PARTS. PART 1: THE OBJECTIVE OF PART 1 IS TO DETERMINE WHETHER AMG 160 IN COMBINATION WITH ABIRATERONE IS SAFE AND TOLERABLE AND WHETHER IT CAUSES ANY SIDE EFFECTS. THIS STUDY WILL ALSO EVALUATE WHICH DOSES OF AMG 160 IN COMBINATION WITH ABIRATERONE ARE SAFE FOR ADMINISTRATION IN MEN AND ITS EFFECT ON MCRPC. PART 2: THE OBJECTIVE OF PART 2 IS TO DETERMINE WHETHER THE SELECTED DOSE OF AMG 160 FROM PART 1 IN COMBINATION WITH ABIRATERONE IS SAFE AND TOLERABLE AND WHETHER IT CAUSES ANY SIDE EFFECTS.
- PHASE 1B STUDY TO EVALUATE THE SAFETY AND EFFICACY OF AMG 160 IN COMBINATION WITH ABIRATERONE IN SUBJECTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER (MCRPC).
- Code EudraCT: 2020-001305-23
- Protocol number: 20190505
- Promoter: Amgen, S.A.
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