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Phase I clinical trial of RO7589831 in participants with advanced solid tumors.
THE PRIMARY OBJECTIVE OF THIS TRIAL IS TO DETERMINE WHETHER RO7589831 ADMINISTERED AT DIFFERENT DOSES HAS EFFECTS, WHETHER POSITIVE OR NEGATIVE, AS WELL AS WHAT HAPPENS TO RO7589831 ONCE IT ENTERS THE BODY AND HOW IT ACTS IN THE BODY AND ON YOUR DISEASE.
Technical Summary
- OPEN-LABEL PHASE I STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND ANTITUMOR ACTIVITY OF RO7589831 IN PARTICIPANTS WITH ADVANCED SOLID TUMORS WITH HIGH MICROSATELLITE INSTABILITY (MSI-H) AND/OR DEFICIENT MISMATCH REPAIR (DMMR).
- Code EudraCT: 2023-503170-20-00
- Protocol number: VVD-133214-01
- Promoter: Vivideon Therapeutics
- Molecule/Drug: RO7589831
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