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Open-label, multicenter phase Ib study to evaluate the safety, efficacy, and pharmacokinetics of mosunetuzumab in combination with pirtobrutinib in patients with relapsed or refractory chronic lymphocytic leukemia.
THE PURPOSE OF THIS STUDY IS TO TEST DIFFERENT DOSES OF MOSUNETUZUMAB TO SEE IF IT IS SAFE AND TO LEARN HOW THE BODY PROCESSES THE DRUG. MOSUNETUZUMAB WILL BE EVALUATED IN COMBINATION WITH PIRTOBRUTINIB, WHICH IS ANOTHER DRUG CURRENTLY USED TO TREAT CLL.
Technical Summary
- OPEN-LABEL, MULTICENTER PHASE IB STUDY TO EVALUATE THE SAFETY, EFFICACY, AND PHARMACOKINETICS OF MOSUNETUZUMAB IN COMBINATION WITH PIRTOBRUTINIB IN PATIENTS WITH RELAPSED OR REFRACTORY CHRONIC LYMPHOCYTIC LEUKEMIA.
- Code EudraCT: 2024-514152-32-00
- Protocol number: BO45287
* The trials only admit a limited number of patients and are subject to inclusion and exclusion criteria. The specialist who assesses your case will inform you of the conditions required to participate in the clinical trial.

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