Clinical trials
for patients
Learn about available clinical trials
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February 23, 2026MadridIn recruitmentEarly phase
ZWI-ZW191-101 Phase I clinical trial to evaluate ZW191 in participants with advanced solid tumors
The primary objective is to evaluate the safety and tolerability of ZW191 and determine the DMT and DREs of ZW191 in different tumor types. -
February 23, 2026Pamplona/MadridIn recruitmentEarly phase
OZUHN-007 Clinical trial for perioperative treatment with durvalumab plus tremelimumab in patients with resectable hepatocellular carcinoma (HCC)
The main goal of this study, which includes research, is to determine whether the new cancer drug durvalumab given with tremelimumab is safe before surgery. Doctors also want to see if the study drugs cause any delays in surgery due to side effects that participants may experience. Doctors will also analyze the effect that the study drugs have on the tumor and whether the tumor recurs after the combination of the study drugs and surgery. -
February 23, 2026Pamplona/MadridIn recruitment
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February 17, 2026PamplonaIn recruitmentEarly phase
OMTX705-001 Clinical trial with OMTX705, an antibody conjugate against fibroblast activation protein, as monotherapy and in combination with pembrolizumab in patients with advanced solid tumors.
The objective of the study is to investigate the safety and preliminary antitumor activity of the antibody-drug conjugate OMTX705 (ADC OMTX705 linked to a cytotoxic tubulysin) in patients with advanced or metastatic cancer. -
February 17, 2026PamplonaIn recruitment
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February 17, 2026Pamplona/MadridIn recruitment
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February 10, 2026Pamplona/MadridIn recruitment
LOXO-BTK-20030 Clinical trial of pirtobrutinib (LOXO-305) compared with ibrutinib in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (BRUIN-CLL-314)
The objectives of this clinical trial are as follows: - To determine the response of patients with CLL/PLLC to treatment with pirtobrutinib (group A) compared to ibrutinib (group B). - To determine the duration of the beneficial effects of treatment with the study drugs (including how long patients live). - To determine safety and tolerability in group A and group B. - To determine how patients in group A fare compared to those in group B. -
February 10, 2026Pamplona/MadridIn recruitment
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February 4, 2026PamplonaIn recruitment
UCART20X22-01 Clinical trial to evaluate UCART20x22 in patients with relapsed or refractory B-cell non-Hodgkin lymphoma
This study is being conducted to determine: - the safe and tolerable dose of UCART20x22 - the efficacy of UCART20x22 in the treatment of NHLB - how long it takes for the body to eliminate UCART20x22 - how much UCART20x22 reaches the bloodstream This study will also test the safety and effectiveness of different lymphodepletion regimens for patients receiving UCART20x22. Lymphodepletion is a type of therapy that decreases the number of your T cells to make room for the UCART20x22 cells. Three dru... -
February 4, 2026Pamplona/MadridIn recruitmentEarly phase
IOV-LUN-202 Clinical trial of autologous tumor-infiltrating lymphocytes (LN-145) in patients with metastatic non-small cell lung cancer
The objective of this study is to test a new investigational treatment for participants with non-small cell lung cancer.